Men's Health

Sex Hormone binding globulin (SHBG)

Sex Hormone Binding Globulin (SHBG) is a protein produced by the liver that binds tightly to sex hormones, including testosterone, dihydrotestosterone (DHT), and oestradiol (an estrogen), transporting them in the blood in an inactive form. By regulating the amount of free (active) hormones available to body tissues, SHBG plays a crucial role in maintaining hormonal balance.

Test details

Sample type
Blood
Time of day
No specific time required​
Fasting required
No
Results timeframe
Within 7 days
Preparation
No special preparation required​

What's measured in this test

Sex Hormone-Binding Globulin

Controls available sex hormone levels.

Common reasons for testing

  • Evaluating hormonal disorders – Assists in diagnosing conditions related to abnormal androgen levels, such as polycystic ovary syndrome (PCOS) in women or hypogonadism in men.
  • Assessing infertility – Helps determine if SHBG levels are affecting the availability of sex hormones necessary for reproduction.
  • Investigating symptoms of hormone imbalance – Useful in cases of reduced libido, erectile dysfunction, or hirsutism (excessive hair growth) to understand underlying hormonal issues.
    Sex Hormone binding globulin (SHBG) | BODYiQ